Available
SS-31 10mg
- Synthetic research peptide for in-vitro structure & function studies
- Independently HPLC-tested and batch-verified
- Batch-specific Certificate of Analysis included with every order
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Every vial is quality-checked to ensure purity and batch-to-batch consistency.
Verified lab quality
- HPLC-tested to ≥ 99% (HPLC) purity
- Batch-specific Certificate of Analysis
- Stored under controlled laboratory conditions
Research Use Only. Not for human or veterinary use. By purchasing you confirm you are a qualified researcher and accept responsibility for safe, lawful handling.
The peptide SS-31, also known as elamipretide, is an injectable peptide containing four amino acids that was created to serve as a research agent for evaluating mitochondria under controlled experimental conditions. As SS-31 is primarily used as an experimental tool for evaluating mitochondrial bioenergetics and membrane dynamics, it has been cited in many scientific papers reporting its use in research. The SS-31 peptide has been evaluated for its ability to reduce oxidative stress through the stabilization of cardiolipin and support healthy tissue by enhancing electron transfer and membrane fluidity. SS-31 peptides are sold as dry powder, and they are packaged in sealed vials to indicate that they are for research purposes only.
Composition and Technical Information
The SS-31 peptide is chemically defined by the sequence D-Arg-Dmt-Lys-Phe-NH2, making it a synthetic cationic-aromatic tetrapeptide. The chemical formula for the SS-31 peptide is C32H49N9O5, has a molecular weight of 639.8 g/mol and a CAS Registry Number of 736992-21-5. Each sealed vial of SS-31 contains 10 mg to provide consistent analytical results, with the purity of the SS-31 peptide being guaranteed by HPLC testing done in a controlled environment, meeting the criteria for superior quality at ≥99% purity. The technical specifications indicate that the SS-31 peptide, in its lyophilized state, will have a stable shelf life if stored at a temperature of 2ºC–8ºC.
Research Focus Areas
SS-31 is widely studied in laboratory and animal models for the following areas of research:
- Mitochondrial Function: Investigated for its role in supporting mitochondrial efficiency and cellular energy production.
- Oxidative Stress Response: Studied for its ability to interact with pathways related to oxidative stress and cellular protection.
- Cellular Energy Metabolism: Explored in models examining ATP production and energy balance within cells.
- Tissue & Cellular Integrity: Evaluated in research focused on maintaining cell structure and function under stress conditions.
Its association with mitochondrial pathways makes SS-31 valuable for studying cellular energy dynamics and protective mechanisms at the cellular level.
SS-31 Peptide Benefits in Research Contexts
The benefits of using the SS-31 peptide include enhancements in electron transfer efficiency and decreased electron leakage in vitro studies, which make it suitable for cardiolipin protection studies and the study of cristae structure in isolated mitochondria. Additionally, SS-31 can provide support for the recovery of membrane potential in cell culture stress tests, and does not appear to significantly disrupt normal cellular physiology in experimental models.
SS-31 Peptide Dosage Considerations for Labs
Dosing of the SS-31 peptide for research can vary widely, although the cellular studies generally use nanomolar doses to target mitochondria. Preclinical data for SS-31 peptide dosing, for example, 1-5 mg/kg, is typically used by laboratories to standardize experimental dosing in ischemic animal models. SS-31 peptide dosing should follow protocol-specific criteria in order to provide reproducible bioenergetic assay results and is only for research purposes.
Quality and Handling Information
The SS-31 peptide is manufactured at laboratories and is made to research grade standards; packaged securely, protected from light and stored between 2°C–8°C to maintain the lyophilized product integrity. Storage should avoid common freeze-thaw cycles associated with peptide research. Handling should adhere to proper cool dry methods to minimize degradation and support reliable HPLC purity results.
Safety & Compliance Notice
SS-31 is supplied strictly for laboratory research purposes only. It is not intended for human or veterinary use, diagnostic procedures, or therapeutic applications. Users are responsible for ensuring compliance with all applicable local laws and regulations. SS-31 has not been approved for clinical use.
Frequently asked questions
It is examined under laboratory conditions to study mitochondrial biology, bioenergetics, and biochemistry related to mitochondrial physiology. It is intended for Research Use Only.
Independent HPLC testing determines chromatographic purity, and LC-MS analysis identifies molecular structure, allowing to be certain of the test results prior to laboratory experimentation.
A certificate of analysis for each batch would contain information on purity, analytical procedures, molecular structure identification, and batch information among others.
Batch tracking enables scientists to repeat their experiments using material that is backed up by analysis documentation.
Current research literature covers mitochondrial biology, metabolism, oxidative biochemistry, ageing model research, neurosciences research, and energy metabolism studies.
Scientists tend to work with companies that can show their quality control process, independent analytical testing, research documentation, and batch identification among other criteria in UK laboratories.
Technical specifications
The SS-31 10mg research peptide is for use in the laboratory environment under controlled scientific study conditions. Prior to using this product in experiments, researchers must carefully check both the product label and the relevant batch documents.
| Chemical name | SS-31 10mg |
| CAS number | 736992-21-5 |
| Molecular formula | C32H49N9O5 |
| Molecular weight | 639.8 g/mol |
| Purity | ≥ 99% (HPLC) |
| Form | Lyophilised powder |
| Storage | 2°C to 8°C (refrigerated), protect from light |
All specifications, including purity values and analytical test results, should be checked against the Certificate of Analysis for the specific batch supplied.
Certificate of Analysis
Every batch of SS-31 10mg is independently analysed by HPLC, with mass-spec for identity. A batch-specific Certificate of Analysis is supplied with your order, confirming the exact purity of the vial you receive.
Download SS-31 10mg CoA (PDF)
